Dextromethorphan Hydrobromide
Alias: Romilar ; DXM CAS No.: 125-69-9
EINECS No.: 204-750-1
M.F.: C18H26BrNO
M.W.: 352.31
Purity: 98.0%
Appearance: White or kind of white crystalline powder, soluble in water.
Usage: Hormones and Regulation of Endocrine Function of Drug
DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen. Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist. The major metabolite of DXM, dextrorphan, also acts as an NMDA receptor antagonist. In high doses this produces effects similar to, yet distinct from, the dissociative states created by other dissociative anaesthetic. As well, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below that of DXM.
| Test Items | Specification | Test Results |
| Appearance | white or almost white crystalline powder, slightly smelly | white crystalline powder |
| Melting point | 123~127 | 123~125 |
| Specific Rotation | +28°~+30° | +29° |
| Acidity(PH) | 5.2~6.5 | 5.8~6.2 |
| Water | 4.0%~5.5% | 5.0% |
| Residue On Ignition | Not more than 0.1% | Conforms |
| N.N - dimethylaniline | Comply with the standard | Conforms |
| Phenolic Compounds | Comply with the standard | Conforms |
| Related Substance | Comply with the standard | Conforms |
| Assay | Between99.0~102.0% | 99.53% |
| Conclusion | This batch is complies with USP 34. | |
